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January 29, 2009
GALAXY
I admit that I have been negligent in keeping up with all the medical literature. (I will address that issue soon). But until I was looking at the JUPITER trial (more later), and was laughing at the names of related trials, I did not realize what I have been missing. Back in 2002, it was announced that there would be a series of trials "under the umbrella name of the GALAXY program, which aims to enroll over 80,000 subjects from more than 30 countries to test a range of effects of statin therapy." This is the fun side of hubris:
Glossary: Expansion of Selected Trial Acronyms
CELESTIAL - Changes in ELEctrocardiographic Signs of Myocardial Ischemia: a TrIAL with rosuvastatin
COMETS - A Comparative study with rosuvastatin in subjects with METabolic Syndrome
DISCOVERY - Direct Statin COmparison of LDL-C Values: an Evaluation of Rosuvastatin therapY
LUNAR - Limiting UNdertreatment of lipids in ACS with Rosuvastatin
MERCURY I - Measuring Effective Reductions in Cholesterol Using Rosuvastatin therapY
MERCURY II - Measuring Effective Reductions in Cholesterol Using Rosuvastatin therapY
ORBITAL - Open label primary care study: Rosuvastatin Based compliance Initiatives linked To Achievement of LDL goals
STELLAR - Statin Therapies for Elevated Lipid Levels compared Across doses to Rosuvastatin
Notice that all the studies concern just one of the statins. The article also mentions other trials of different statins with less exciting names:
ENHANCE - Ezetimibe and Simvastatin in Hypercholesterolemia Enhances Atherosclerosis Regression
SEAS - Simvastatin and Ezetimibe in Aortic Stenosis
| By Robert Maddox | 12:29 PM